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Updated: Jun 28, 2025

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缺陷的Lamtor5通过放松v-ATPase和溶酶体酸化的调节导致自身免疫

Wei Zhang1, Zhou Sha1, Yunzhe Tang1

  • 1School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210046, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|April 19, 2024
PubMed
概括

晚期内/溶酶体适配体,MAPK和mTOR激活器5 (Lamtor5) 缺乏会损害溶酶体功能和mTORC1激活,导致全身性红斑狼 (SLE) 和自身免疫性疾病.

关键词:
这是自身免疫力.在LAMTOR5中,使用了LAMTOR5.lysosome 溶解酶体是如何形成的v-ATPasease 的使用情况.

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