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Updated: Jun 28, 2025

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临床试验的贝叶斯式设计使用尺度变换功率先前的尺度

Xinxin Chen1, Brady Nifong2, Ethan M Alt1

  • 1Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Journal of biopharmaceutical statistics
|April 19, 2024
PubMed
概括

本研究引入了一种新的贝叶斯方法来确定样本大小 (SSD),使用具有不同结果的历史数据. 部分借款规模转换前功率 (straPP) 框架使得当历史和新研究结果分歧时,更准确的试验设计成为可能.

关键词:
贝叶斯样本大小的确定贝叶斯样本大小的确定不同质的终点点.信息 借款 信息 借款时间到事件数据.

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