[与前列腺癌中的血管生成和茎状特征相关的标志物的研究进展]
1Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China .
Zhonghua nan ke xue = National journal of andrology
|April 19, 2024
概括
前列腺癌 (PCa) 复发,转移和耐药性与瘤血管生成和癌症干系有关. 本综述探讨了这些因素如何创造一个有害的循环,推动PCa的进展和死亡率.
科学领域:
- 在瘤学瘤学.
- 癌症生物学 癌症生物学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
关键词:
前列腺癌;血管新生;茎状;相关概念视频
Mechanism of Angiogenesis
5.4K
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
5.4K
Cancer Stem Cells and Tumor Maintenance
4.9K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
4.9K


