自然酶口水的有效性:一个随机对照试验
Thao Liang Chiam1, Jowayne Choo2, Atika Ashar1
1Faculty of Dentistry, The National University of Malaysia (UKM), Kuala Lumpur, Malaysia.
Clinical oral investigations
|April 19, 2024
概括
天然酶口水有效地治疗了异口症的症状,改善了口腔干燥的感知和唾液流. 这种安全且耐受良好的治疗方法为患有口腔干燥的患者提供了有前途的选择.
科学领域:
- 生物医学科学 生物医学科学
- 口腔健康 口腔健康
- 药理学 药理学是指药理学的学科.
背景情况:
- Xerostomia (口腔干燥) 显著影响生活质量.
- 天然酶口水正在被探索作为一种唾液替代品,用于施口症管理.
- 之前的研究表明了潜在的益处,需要进行临床评估.
研究的目的:
- 为了评估天然酶口水在治疗异口症时的有效性.
- 在一个随机对照试验中,将天然酶口水与胺口水进行比较.
- 为了评估异口腔症状,口腔干燥和唾液流量率的改善.
主要方法:
- 进行了一项双盲,并行组随机对照试验,其中49名成年参与者患有异口症.
- 参与者接受了天然酶口水或胺口水两周,每天冲洗四次.
- 评估包括 Xerostomia 库存,临床口腔干燥评分 (CODS) 和唾液流速测量.
主要成果:
- 天然酶口水组从基线显示出异口症症状的显著减少.
- 在口腔干燥,口腔运动功能和夜间口渴的认知知觉方面观察到改善.
- 在干预组 (p < 0.05) 中,CODS和静止唾液流速的显著改善.
结论:
- 天然酶口水有效地改善了异口症的迹象和症状.
- 口水是潜在的有效,耐受性很好,对于异口症患者是安全的.
- 这种天然酶配方为治疗口腔干燥症提供了可行的治疗选择.
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