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Updated: Jun 28, 2025

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细菌生物发光成像技术发展的进展

Tianyu Jiang1, Xiaoyu Bai1,2, Minyong Li3

  • 11Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, Shandong, China.

Annual review of analytical chemistry (Palo Alto, Calif.)
|April 19, 2024
PubMed
概括

工程生物发光细菌为体内生物发光成像 (BLI) 提供了强大的工具. 这些细菌能够实时跟踪感染,益生菌和药物查,推进细菌成像应用.

关键词:
生物发光是一种生物发光.工程设计的生物发光细菌在活体中成像成像光酶是一种光酶.路西费林是一种光剂.

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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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