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Updated: Jun 28, 2025

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
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Published on: August 14, 2017

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甘氨酸的决定因素调节了对维贝尔-帕拉德体的VWF贩运

Ellie Karampini1, Dearbhla Doherty1, Petra E Bürgisser2

  • 1Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.

Blood advances
|April 19, 2024
PubMed
概括

在·威尔布兰德因子 (VWF) 上发生的改变的O链 glycans (OLGs) 损害了其生物合成和内皮细胞 (ECs) 的分泌. 这影响了VWF多元化,韦贝尔-帕拉德体形成和静血功能.

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