互动和竞争的肠道吸收,铁,铜和在肠道粘液层的肠道吸收
Vincent Einhorn1, Hajo Haase1, Maria Maares2
1Technische Universität Berlin, Department of Food Chemistry and Toxicology, Straße des 17. Juni 135, Berlin 10623, Germany; Trace Age-DFG Research Unit on Interactions of Essential Trace Elements in Healthy and Diseased Elderly, Potsdam-Jena-Wuppertal, Berlin, Germany.
概括
由粘膜组成的肠粘液层对于吸收铁和等微量元素至关重要. 这些元素的竞争始于粘液,影响了它们的生物利用性.
科学领域:
- 生物化学 生物化学
- 人体生理学 人体生理学
- 胃肠病学 胃肠病学
背景情况:
- 微量元素 (,,铜,铁) 对于生理功能至关重要.
- 以前的研究重点是用于微量元素吸收的运输蛋白.
- 肠粘液层在微量元素吸收中的作用不太清楚.
研究的目的:
- 审查胃肠道粘膜与微量元素 (铁,,,铜) 之间的相互作用.
- 总结当前的知识,并确定有关素对微量元素生物可用性和竞争的影响的差距.
主要方法:
- 对胃肠道粘膜和微量元素相互作用研究的文献综述.
- 对金属-素相互作用及其对吸收的影响现有数据的分析.
主要成果:
- 胃肠道粘膜对于保持微量元素在肠道中的溶解性至关重要.
- 素有助于肠细胞吸收铁,,和铜.
- 有证据表明,微量元素吸收的竞争发生在粘液层.
结论:
- 肠道粘膜在微量元素恒温中发挥着重要作用.
- 微量元素的竞争始于粘液层,影响生物可用性.
- 需要进一步的研究来充分阐明粘素和微量元素的相互作用.
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