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Updated: Jun 28, 2025

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PFKFB3通过影响ERα稳定性来调节乳腺癌瘤发生和Fulvestrant敏感性

Wenzhi Jia1, Qianyun Wu1, Mengqin Shen1

  • 1Department of Nuclear Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cellular signalling
|April 19, 2024
PubMed
概括

高水平的PFKFB3通过稳定ERα,使雌激素受体阳性乳腺癌的预后恶化. 通过PFK158抑制PFKFB3,提高了富勒弗兰特的有效性,提供了一个新的治疗策略.

关键词:
乳腺癌是什么? 乳腺癌是什么这就是ERα ERα.PFKFB3B3 是一个很好的选择.蛋白质的稳定性 蛋白质的稳定性一个叫做STUB1的人.

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