在患有症状的退伍军人中,在9/11后军事部署后肺功能的纵向变化
Lauren M Zell-Baran1, Silpa D Krefft2, Matthew Strand3
1National Jewish Health, Division of Environmental and Occupational Health Sciences, Denver, CO, USA; Department of Epidemiology, Colorado School of Public Health, Colorado, Aurora, USA.
暴露在燃烧坑和灰尘中的退伍军人可能会患上与部署相关的呼吸道疾病 (DRRD). 患有远端肺部疾病 (DDLD) 的人随着时间的推移显示肺功能下降,这表明战斗暴露的长期影响.
科学领域:
- 职业医疗 职业医疗 职业医学
- 环境健康 环境健康
- 肺部病理学 肺部病理学
背景情况:
- 军事部署到西南亚和阿富汗 (SWA) 涉及暴露于燃烧坑烟雾,灰尘和柴油废气等危害.
- 这些暴露与部署相关的呼吸道疾病 (DRRD) 和潜在的长期肺功能下降有关.
研究的目的:
- 评估部署暴露对SWA部署退伍军人的肺功能的影响.
- 根据特定的DRRD诊断和暴露强度来确定肺功能中的差异.
主要方法:
- 评估了219名SWA部署退伍军人的肺功能,他们正在接受职业肺病评估.
- 利用线性混合模型来分析随时间变化的肺功能.
- 根据部署暴露和DRRD诊断,评估肺功能差异.
主要成果:
- 大多数有症状的退伍军人暴露率高,但初始螺旋测量正常.
- 常见的DRRD包括涉及小气道的遥远肺部疾病 (DDLD, 41%) 和与部署相关的喘 (DRA, 13%).
- 患有DDLD和DRA的退伍军人表现最低的螺旋量,仅患有DDLD的退伍军人每年FEV1/FVC下降0.2%.
结论:
- 较高的吸入暴露强度与部署后肺功能下降相关.
- 远距离肺部疾病 (DDLD) 与FEV1/FVC比率的显著纵向下降有关.
- 其他DRRD诊断没有显示类似的纵向肺功能下降.
更多相关视频
06:11Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
Published on: February 9, 2022
02:09Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
相关概念视频
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
