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Updated: Jun 28, 2025

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells
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通过血清素受体5-HT7RR激活激酶CDK5的结构决定因素

Jana Ackmann1, Alina Brüge1, Lizaveta Gotina2,3

  • 1Department of Cellular Neurophysiology, Institute for Neurophysiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

Cell communication and signaling : CCS
|April 19, 2024
PubMed
概括

向血清素受体7 (5-HT7R) 和循环素依赖激酶5 (CDK5) 相互作用可以减少神经退行性疾病中的Tau病理. 这项研究确定了这种相互作用的关键结构元素,为新疗法铺平了道路.

关键词:
计算建模计算建模循环素依赖性激酶5 (CDK5) 是一种互动界面 互动界面 互动界面蛋白质蛋白质复合体 蛋白质蛋白质复合体血清素受体7 (5-HT7R) 是一种局部导向的突变发生.陶蛋白 (Tau) 和陶病症

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