在患有关节炎的儿科患者的膝盖MRI上测量结膜厚度:对比是必要的吗?
Atsuhiko Handa1, M Alejandra Bedoya2, Jade Iwasaka-Neder2
1Department of Radiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA. atsuhiko.handa@childrens.harvard.edu.
Pediatric radiology
|April 19, 2024
概括
非增强型MRI相当于对比增强型MRI,用于评估青少年异常性关节炎 (JIA) 中的突结膜厚度. 虽然对比提高了阅读器可靠性,但未增强的扫描为此JIA评估提供了可比的诊断准确性.
科学领域:
- 放射学 放射学是一门学科.
- 儿科成像学 儿科成像学
- 类风湿病学 类风湿病学
背景情况:
- 与对比度增强的磁共振成像 (MRI) 是评估青少年异常性关节炎 (JIA) 中肌炎的标准.
- 磁力共振成像技术的进步使得在没有对比剂的情况下可以识别突.
- 这项研究研究了未增强型MRI在JIA评估中的有效性.
研究的目的:
- 为了确定无增强型MRI与对比增强型MRI在测量突结膜厚度方面的等价性.
- 为了比较JIA患者的两个MRI技术之间的诊断准确性和可靠性.
主要方法:
- 对小儿JIA患者 (21岁以下) 进行膝盖MRI (1.5T或3T) 具有或没有对比的回顾性研究.
- 两位放射科医生独立测量了6个膝盖部位的突结膜厚度,使用数值和顺序 (JAMRIS) 评分.
- 使用一致性相关系数 (CCC) 进行了等价性测试和读者间/读者内可靠性分析.
主要成果:
- 在所有6个位点 (P<0.05) 中,在未增强和增强对比度的MRI之间,在突结膜厚度评估中证明了等价性 (P<0.05).
- 在读器内可靠性中等至高 (CCC 0.50-0.89),在未增强的扫描中,十字带部位的可靠性较低.
- 与对比度增强 (CCC 0.64) 的MRI相比,没有增强的MRI (CCC 0.47) 的读者间可靠性较低.
结论:
- 未增强的膝盖MRI相当于对比增强的MRI,用于使用常规序列评估JIA中的突厚度.
- 虽然对比剂提高了读者之间的可靠性,但未增强的MRI为JIA突炎评估提供了可行的替代方案.
- 未来的研究可能会探索提高JIA无增强型MRI评估中读者间可靠性的策略.
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