柔性晶体镜查的低估的预防作用:随机试验的再分析和元分析
Hermann Brenner1,2, Thomas Heisser3,4, Rafael Cardoso3
1Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), INF 581, Heidelberg, 69120, Germany. h.brenner@dkfz.de.
灵活的半导体镜 (FS) 查显著降低了结直肠癌 (CRC) 的发生率. 一个FS可以在15年内在55-64岁的个体中预防多达三分之二的远端CRC病例.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 结肠直肠癌 (CRC) 查对于早期检测和预防至关重要.
- 与结肠镜相比,灵活的半导体镜 (FS) 是一种不那么侵入性的,具有成本效益的查选择.
- 之前的试验报告了与FS的温和CRC发病率降低,可能高估了包括流行癌症的好处.
结论:
- 在55岁至64岁之间提供的一次灵活的西格莫显微镜查显著降低了CRC发病率.
- 在15年内,FS查可以预防大约三分之二的远端CRC病例.
- 重新分析强调了FS在预防发生的结直肠癌方面的重大影响.
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