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在美国成年人中,膀过活和抑郁之间的关联:NHANES 2005-2018的横截面研究
Yuyang Zhang1, Xu Wu1, Guodong Liu1
1Department of Urology, The First Affiliated Hospital of Anhui Medical University, Anhui Province, China; Institute of Urology, The First Affiliated Hospital of Anhui Medical University, Anhui Province, China; Anhui Province Key Laboratory of Urological and Andrological Diseases Research and Medical Transformation, Anhui Medical University, Anhui Province, China.
过度活跃的膀 (OAB) 与抑郁症有很强的联系. 增加OAB严重程度显著增加患抑郁症症状的风险,突出了综合护理的需要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 过度活跃的膀 (OAB) 和抑郁症是普遍存在的疾病.
- 现有的研究表明OAB与抑郁症之间存在联系,但大规模研究有限.
研究的目的:
- 通过使用大型数据集,调查膀过活和抑郁症状之间的关联.
- 探索OAB严重程度与抑郁症存在之间的关系.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 数据库 (2005-2018) 的数据.
- 通过过度活动膀症状评分 (OABSS > 3) 和通过患者健康问卷 (PHQ-9 ≥ 10) 确定OAB和抑郁症.
- 雇佣了调查加权后勤回归模型,包括子组和光滑曲线分析,以评估关联.
主要成果:
- 总共有6612名参与者被分析,其中1005人被诊断为OAB.
- 在对共变量进行调整后,在OAB和抑郁症之间发现了显著的积极关联 (OR:2.89).
- 随着OAB的严重程度,抑郁症的风险逐渐增加:轻度 (OR:2.76),中度 (OR:3.79),严重 (OR:5.21).
结论:
- 膀过活和抑郁症之间存在着强烈的联系.
- 抑郁症的风险随着OAB严重程度的增加而升级.
- 临床医生应考虑对患有抑郁症状的患者进行OAB症状评估,并监测OAB患者的心理健康状况.
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