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相关概念视频

Kidney Structure01:45

Kidney Structure

69.6K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
69.6K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

1.0K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.0K
Internal Anatomy of the Kidney01:12

Internal Anatomy of the Kidney

1.6K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
1.6K
Introduction to Urinary System01:13

Introduction to Urinary System

2.5K
The urinary system consists of two kidneys, two ureters, the urinary bladder, and the urethra.
The kidneys are bean-shaped organs located in the retroperitoneal space, on either side of the vertebral column, between the T12 and L3 vertebrae. They are partially protected by the rib cage and surrounded by perirenal fat, which provides cushioning. They are responsible for urine formation and play critical roles in regulating blood pressure, electrolyte levels, and hormone production. The ureters...
2.5K

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Perspectives of Patients on the Kidney Transplant Waitlist Regarding Willingness to Undergo Xenotransplantation.

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Pathologic evaluation of pig kidney and heart xenografts: 2024 recommendations from the Banff Xenotransplantation Pathology Working Group.

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相关实验视频

Updated: Jun 28, 2025

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
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Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

Published on: August 21, 2020

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一个支持人类生理学的猪脏.

Stuart J Knechtle1, Joseph M Ladowski1, Jean Kwun1

  • 1Department of Surgery, Duke University, School of Medicine, Durham, North Carolina, USA.

Kidney international
|April 20, 2024
PubMed
概括

异种移植对患有功能衰竭的患者来说是有前途的. 一项研究表明,猪成功地支持了脑死亡的人类7天,为克服捐赠器官短缺提供了希望.

科学领域:

  • 移植生物学 移植生物学
  • 腎臟病學 (nephrology) 是一種醫學專業.
  • 手术创新 在外科创新.

背景情况:

  • 全球捐赠脏短缺需要为功能衰竭患者提供替代解决方案.
  • 使用动物器官的异种移植是解决这一关键需求的潜在策略.
  • 已故模型为推进临床异种移植提供了宝贵的见解.

研究的目的:

  • 评估移植猪脏在人类接受者的生理功能和生存能力.
  • 评估异种移植作为衰竭维持生命治疗的潜力.
  • 为了收集补充临床前研究的数据,用于临床脏异种移植的发展.

主要方法:

  • 将一种转基因猪移植到一个脑死亡的人类模型中.
  • 监测关键的生理参数,以评估功能.
  • 使用死者模型来模拟和研究异种移植结果.

主要成果:

  • 移植的猪脏显示了持续维持生命的生理功能,持续7天.
  • 该研究提供了成功整合和功能在人类接受者的证据.
  • 收集的数据支持猪异种移植的可行性.

结论:

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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

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5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
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Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

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5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
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5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

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  • 猪脏异种移植可以在人类模型中实现维持生命的生理功能.
  • 遗传模型对于评估异种移植疗效和安全非常有价值.
  • 这项研究有助于开发临床异种移植策略.