在低风险妇女中进行过早分娩查的随机试验 - 过早分娩查研究
Gabriele Saccone1, Giuseppe Maria Maruotti1, Maddalena Morlando2
1Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy (Drs Saccone, Maruotti, and Sarno; Ms Gragnano; Drs Bartolini, Borrelli, Locci, and Guida).
American journal of obstetrics & gynecology MFM
|April 20, 2024
概括
在低风险怀孕中,通用透阴超声波宫长度查并没有显著降低早产率. 该研究发现,查和对照组之间的早产发病率没有差异.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 诊断性超声波 超声波 超声波 超声波
背景情况:
- 过早分娩是围产期发病率和死亡率的主要原因.
- 在低风险怀孕中,通用跨阴道超声波子宫长度查的有效性仍然不确定.
研究的目的:
- 为了评估中期的全身性阴道超声波宫长度查是否减少早产 (<37周) 在无症状单胎怀孕没有过早分娩的历史.
主要方法:
- 一个多中心,非盲目的随机试验,涉及1334个无症状单项怀孕,没有先前的自发早产.
- 参与者被随机分配到宫长度查计划或对照组.
- 查组接受了通过阴道的超声波来测量宫长度;长度≤25毫米的组接受了阴道孕激素和宫.
主要成果:
- 在<37周的早产发生在查组的7.5%,对照组的8.7% (RR,0.86;95% CI,0.59-1.25) 中.
- 在各种妊娠年龄切线 (<34, <32, <30, <28, <24周) 中没有观察到早产率的显著差异.
结论:
- 全球性三月中旬阴道超声波宫长度查,以及治疗短宫,并没有显著降低低风险怀孕中早产的发生率.
- 这些发现表明,这种查计划可能无法有效地减少这一群体的早产.
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