患有的儿童的长期神经心理轨迹:手术是否会阻止下降?
Maria H Eriksson1,2,3, Freya Prentice1,2, Rory J Piper1,4
1Developmental Neurosciences Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.
Brain : a journal of neurology
|April 20, 2024
概括
手术可以阻止或逆转患有耐药的儿童的认知衰退. 建议进行早期的手术干预,以改善神经心理功能并防止进一步下降.
科学领域:
- 儿科神经学 儿科神经学
- 神经心理学 神经心理学
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 耐药性经常导致儿童的神经心理障碍.
- 之前关于手术对这些障碍的影响的研究已经产生了不一致的结果.
研究的目的:
- 研究手术对儿童神经心理功能的长期影响.
- 确定手术是否可以改变与耐药相关的认知衰退的轨迹.
主要方法:
- 一项回顾性队列研究,涉及1990年至2018年期间接受手术的500名儿童.
- 通过回归分析,分析手术前后收集的神经心理数据 (智商和学业成绩).
主要成果:
- 孩子们在手术前经历了神经心理功能显著下降.
- 在小组层面上,在手术后立即没有观察到神经心理表现的显著变化.
- 手术后实现了无发作的儿童表现出神经心理表现的改善,并在长期随访期间持续改善.
- 手术后停止服用抗发作药物与更大的认知和学术收益有关.
结论:
- 手术可能会阻止和逆转患有耐药的儿童神经心理功能下降的情况.
- 实现自由和使药物停止成为改善认知结果的关键因素.
- 建议对患有焦点的儿童进行手术的早期考虑,以预防或减轻神经心理缺陷.
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