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Updated: Jun 28, 2025

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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N4BP1作为一个依赖于二分化的线性泛素读取器,它调节TNF信号传递.

Katarzyna W Kliza1,2, Wei Song3,4, Irene Pinzuti3

  • 1Institute of Biochemistry II, Goethe University School of Medicine, Frankfurt (Main), Germany. katarzyna.kliza@mpi-dortmund.mpg.de.

Cell death discovery
|April 20, 2024
PubMed
概括

结合NEDD4的蛋白1 (N4BP1) 作为一种新的线性泛素读者,调节炎症和细胞死亡. 其独特的二分化依赖模块 (LUBIN) 控制瘤亡因子受体1 (TNFR1) 信号持续时间.

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