使用马尔科夫模型评估英国NHS糖尿病预防计划的长期成本效益
1Health Organisation, Policy and Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Suite 12, Floor 7, Williamson Building, Oxford Road, Manchester, M13 9PL, UK. emma.mcmanus@manchester.ac.uk.
PharmacoEconomics - open
|April 20, 2024
概括
国家卫生服务 (NHS) 糖尿病预防计划 (DPP) 是一个具有成本效益的干预措施,节省资金并改善非糖尿病高血糖症患者的健康结果. 建议继续投资以支持这一重要的公共卫生倡议.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 预防医学 预防医学
背景情况:
- 英国于2016年启动了NHS糖尿病预防计划 (DPP),这是预防糖尿病的最大的国家计划.
- 本研究评估了NHS DPP的长期经济可行性和有效性.
研究的目的:
- 评估NHS糖尿病预防计划 (DPP) 与常规护理相比的长期成本效益.
- 提供证据支持对国家糖尿病预防战略的持续投资.
主要方法:
- 采用35年的马尔科夫队列状态过渡模型,将NHS DPP与非糖尿病高血糖症患者的通常护理进行比较.
- 概率分析,包括10,000次蒙特卡洛模拟和灵敏度分析,从卫生系统的角度进行,使用英国英 (£).
主要成果:
- 预计NHS DPP将主导常规护理,平均产生40.8个增量质量调整寿命年 (QALY),每1000人节省135,755英.
- 在35年的时间里,该计划预计将节省7140万英,并为2020年4月之前收到的转诊提供21472个额外的QALY.
- 在各种敏感性分析中,结果保持稳健,表明该计划的成本效益.
结论:
- 英国国民健康局的糖尿病预防计划 (DPP) 显示出显著的成本效益,并且可能节省成本.
- 这些发现支持糖尿病预防计划的持续投资和重新启动.
- 美国NHS DPP有效地预防糖尿病并改善人口健康状况.
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