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疫苗接种和查策略以加速挪威的宫癌消除:基于模型的分析分析
Allison Portnoy1,2, Kine Pedersen3, Jane J Kim4
1Department of Global Health, Boston University School of Public Health, Boston, MA, USA. aportnoy@bu.edu.
British journal of cancer
|April 20, 2024
概括
仅仅增加HPV疫苗接种率不太可能加速挪威的宫癌消除速度. 针对未经查的人群提供了一个更快的途径,以消除宫癌和更大的健康益处.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 在瘤学瘤学.
背景情况:
- "EVEN FASTER"概念旨在减少人类乳头瘤病毒 (HPV) 循环.
- 消除宫癌 (CC) 是全球卫生优先事项.
研究的目的:
- 评估HPV疫苗接种策略对挪威CC发病率和消除时间的影响.
- 将仅接种疫苗的干预措施与基于CC查的策略进行比较.
主要方法:
- 使用基于模型的方法来模拟各种HPV疫苗接种和CC查场景.
- 场景包括疫苗接种率的逐步增加以及查频率和遵守率的变化.
- 评估的结果是年龄标准化发病率 (ASR),终身CC风险和结肠镜转诊.
主要成果:
- 减少查频率的疫苗接种策略降低了ASR,但没有加速CC消除.
- 增加查遵守率显示,有可能加速消除和改善ASR.
结论:
- "EVEN FASTER"的疫苗成分不太可能加速挪威的CC消除,但可能会降低人口ASR.
- 针对CC查的不足和从未查者,可以实现比评估的疫苗接种策略更快的消除和更大的健康益处.
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