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在口腔癌的口腔外科手术中出现第一咬综合征
Paul R Wistermayer1, Adam E Brown2, Taylor B Cave1
1Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Phoenix, Arizona, USA.
概括
在口腔癌经口腔手术后的第一次咬伤综合征 (FBS) 与对腔空间操纵有关. 大多数患者出现症状缓解,这表明有针对性的手术方法可以减轻这种并发症.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术瘤学手术瘤学
- 头部和部手术 头部和部手术
背景情况:
- 首次咬伤综合征 (FBS) 是口腔平细胞癌 (OPSCC) 经过口腔外科手术 (TOS) 后的一种罕见并发症.
- 在TOS后FBS的风险因素尚未明确,需要进一步调查以改善患者的治疗结果.
研究的目的:
- 在接受OPSCC的TOS患者中确定与FBS发展相关的风险因素.
- 阐明手术技术与FBS发生率之间的关系.
主要方法:
- 在第三级护理中心接受OPSCC的TOS患者的回顾性图表审查.
- 对人口统计数据,并发病,瘤特征,手术细节和辅助治疗的分析.
- 统计分析包括费舍尔的精确测试,克鲁斯卡尔-瓦利斯的等级总和测试和多变量后勤回归来识别显著的风险因素.
主要成果:
- 在89名符合条件的患者中,有7名 (7.9%) 患有FBS.
- palatine瘤的位置, styloglossus/stylopharyngeus肌肉的切除,以及对关节脂肪的操纵与FBS有关.
- 在调整瘤位置后,对关脂肪的操纵仍然是一个显著的独立风险因素;86%的受影响患者经历了解决.
结论:
- 对喉空间的操纵是OPSCC的TOS后发展FBS的一个独立风险因素.
- 需要进一步的研究来证实这些发现,并探索预防策略.
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