抑郁症介导着暴露于耻辱和艾滋病毒感染者在低资源环境中的药物坚持之间的关系:一个结构方程建模方法
Sahabi Kabir Sulaiman1, Muhammad Sale Musa2, Fatimah Isma'il Tsiga-Ahmed3
1Department of Medicine, Yobe State University Teaching Hospital, Damaturu, Nigeria. sahabikabir25@gmail.com.
Journal of behavioral medicine
|April 21, 2024
概括
抑郁症调解了艾滋病毒感染者 (PLHIV) 之间耻辱和药物不服药之间的联系. 减少污名的暴露是改善PLHIV的坚持的关键.
科学领域:
- 医学和健康科学医学和健康科学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 耻辱和抑郁症是艾滋病毒感染者 (PLHIV) 面临的重大挑战.
- 药物坚持对于管理艾滋病毒和预防传播至关重要.
- 了解耻辱,抑郁和坚持之间的相互作用对于有效的艾滋病毒治疗至关重要.
研究的目的:
- 调查抑郁症在耻辱和抗逆转录病毒疗法 (ART) 药物坚持之间关系中的调解作用.
- 确定影响尼日利亚北部PLHIV人口中耻辱和坚持的因素.
主要方法:
- 一项涉及353名艾滋病毒感染者 (PLHIV) 的横截面研究,来自尼日利亚北部的六个ART诊所.
- 结构方程建模 (SEM) 用于分析耻辱,抑郁和ART药物坚持之间的关系.
- 在分析中调整了社会人口统计学特征.
主要成果:
- 经历过更高水平的耻辱感与药物坚持程度降低有关.
- 抑郁症部分调解了耻辱和药物坚持之间的关系,解释了35.6%的关联.
- 作为女性和居住在城市地区与较低的耻辱感有关,而作为女性也与更高的坚持有关.
结论:
- 抑郁症在污名化对PLHIV药物坚持的负面影响中发挥着重要的调解作用.
- 针对减少耻辱的干预措施对于改善艾滋病病毒感染者的ART坚持和健康结果至关重要.
- 在艾滋病毒管理计划中,解决抑郁症等精神健康并发症至关重要.
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