通过抑制NF-κB酸化和核转位,EGCG抑制T细胞的PD-1表达

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Updated: Jun 28, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

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Zhong-Da Li1, Fangfang Liu1, Yanqiao Zeng1

  • 1Laboratory of Inflammation and Vaccines, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Laboratory of Immunology and Nanomedicine, and China-Italy Joint Laboratory of Pharmacobiotechnology for Medical Immunomodulation, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

International immunopharmacology
|April 21, 2024
PubMed
概括

甲基-3-酸盐 (EGCG) 是一种茶叶聚,通过阻断NF-κB信号传递,抑制T细胞的编程细胞死亡1 (PD-1). 这增强了抗瘤免疫力和T细胞介导的瘤细胞亡.

关键词:
这是一种抗瘤药物.对于 EGCG 的情况来说,这是一项非常重要的决定.在 NF-κBB 中.在PD-1中使用PD-1.在T细胞,T细胞.

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