相关实验视频

Updated: Jun 28, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

前庭心肌病预测了中风患者的功能结果和死亡率

Xinjing Liu¹, Yuying Wang¹, Lan Ding¹

¹Department of Neurology, The First Affiliated Hospital of Zhengzhou University.

Journal of atherosclerosis and thrombosis

|April 21, 2024

概括

心房心肌病症 (ACM) 预测非心血管栓塞性中风 (NCS) 患者的结果不佳. 较高的NT-pro BNP水平表明,中风后死亡风险较高.

科学领域:

心脏病学心脏病学
神经学神经学
生物标志物生物标志物

背景情况:

心房心肌病变 (ACM) 是一种以心房功能障碍为特征的疾病.
非心血管栓塞性中风 (NCS) 对患者的预后构成重大风险.
评估NCS中长期结果的预测因素对于患者管理至关重要.

研究的目的:

评估被诊断为非心血管栓塞性中风 (NCS) 的患者心房心肌病变 (ACM) 的预后意义.
确定潜在的生物标志物来预测NCS患者的功能结果和死亡率.

主要方法:

在2019年1月至2020年12月期间,有望招募1,346名NCS患者.
基于NT-pro BNP水平 (>250 pg/ml) 或V1中的P终端力 (PTFV1) (≥5000μV·ms) 的ACM诊断.
后勤和考克斯回归分析用于评估ACM与功能表现差 (mRS 3-6) 或2年死亡率之间的关联.

主要成果:

在22.2%的患者中诊断出ACM (n=299).
ACM显著与功能性结果差 (aOR:2.01;p<0.001) 相关.
较高的NT-pro BNP (>250 pg/ml) 预测会增加所有原因的死亡风险 (aHR:2.51;p=0.001).

结论:

心房心肌病变 (ACM) 可能成为非心血管栓塞性中风 (NCS) 患者长期不良功能结果的新型预测因素.
升高的N-终端脑前性尿素 (NT-pro BNP) 水平与NCS后因任何原因死亡的风险更高有关.
建议进行进一步的多中心验证,以确认这些预后影响.

关键词:

大心室心肌病变性心脏病变.功能性结果的结果.死亡率死亡率死亡率 NT-pro BNP 美国国家银行非心血管血栓性中风在PTFV1中使用.

更多相关视频

Myocardial Infarction and Functional Outcome Assessment in Pigs

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

相关概念视频

Imbalances in Cardiac Output

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...

Pathophysiology of Heart Failure

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...