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Updated: Jun 28, 2025

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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基于多酶类聚氧甲酸的单原子酶,用于通过酸触发的非毒性转化为毒性的癌症特异疗法

Xiyang Ge1, Yiyan Yin1, Xiaoni Wang1

  • 1Country Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, P. R. China.

Small (Weinheim an der Bergstrasse, Germany)
|April 21, 2024
PubMed
概括

基于的多氧甲酸单原子酶 (Mn-POM SAEs) 通过在酸性瘤环境中激活,提供瘤特异性化学动力学疗法 (CDT). 这种方法通过产生反应性氧物种和破坏细胞过程来增强癌症治疗.

关键词:
酸引发的无毒性转毒性过渡.具有多酶类活动的多酶类活动.聚氧甲基酸盐是一种多氧甲基酸盐.单原子酶是一种单原子酶.治疗机制的治疗机制

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