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[关于膜性病的遗传研究现状和前景]

X F Hu1, J Y Xie1

  • 1Department of Nephrology, Institute of Nephrology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China.

Zhonghua yi xue za zhi
|April 21, 2024
PubMed
概括

全基因组关联研究 (GWAS) 提供了对原发性膜性病 (PMN) 病原和个体差异的新见解. 这种方法推进了精准医学,以更好地诊断和治疗PMN.

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...