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Updated: Jun 28, 2025

Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro
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向二维基因酶的OTUB1通过调节PDGFRβ来保护动脉样硬化中的血管光滑肌细胞

Fei Xu1,2,3,4, Han Chen2,3,4, Changyi Zhou2,3,4

  • 1Department of Cardiology and Laboratory of Heart Valve Disease, West China Hospital, Sichuan University, Chengdu, 610041, China.

Frontiers of medicine
|April 21, 2024
PubMed
概括

准OTUB1,一个二维基因酶,可以防止血管光滑肌细胞 (VSMC) 现型切换和动脉样硬化进展. 沉默OTUB1稳定了斑块,并通过促进PDGFRβ降解来减少心血管功能障碍.

关键词:
在OTUB1上.这是PDGFRββ.动脉样硬化 动脉样硬化没有二维基因酸酶.无处不在的无处不在关系血管光滑肌肉细胞细胞

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