在日本的医疗信息数据库网络 (MID-NET®) 中检测胃肠道穿孔病例的检测算法
Masatoshi Tanigawa1, Mei Kohama2, Kaori Hirata2
1Clinical Research Support Center, Kagawa University Hospital, 1750-1 Ikenobe, Miki-Cho, Kita-Gun, Kagawa, 761-0793, Japan. tanigawa.masatoshi.k6@kagawa-u.ac.jp.
Therapeutic innovation & regulatory science
|April 21, 2024
概括
这项研究开发了在日本医学信息数据库网络 (MID-NET®) 中识别胃肠道穿孔 (GIP) 的算法. 最好的算法平衡了准确性和灵敏性,以改善药物监测.
科学领域:
- 药物监督 药物监督 药物监督
- 医疗信息学 医疗信息学
- 医疗数据分析 医学数据分析
背景情况:
- 医疗信息数据库网络 (MID-NET®) 是日本重要的药监资源.
- 目前在MID-NET®中没有确立的算法用于识别胃肠道穿孔 (GIP).
研究的目的:
- 在MID-NET®中开发和评估用于识别GIP的算法.
- 评估不同识别算法的积极预测值 (PPV) 和相对灵敏度 (rSn) 之间的权衡.
主要方法:
- 评估了12种结合ICD-10代码和GIP治疗程序的算法.
- 利用来自三个机构的住院患者数据,包括ICD-10代码,CT扫描信息,抗菌素处方和手术代码.
- 在特定机构确定PPV和评估rSn.
主要成果:
- 在各个算法中观察到PPV和rsn之间的权衡.
- 将ICD-10代码与诊断和程序代码结合在一起的算法改进了PPVs.
- 结合ICD-10代码,CT扫描,抗菌信息和80个操作代码的算法实现了最佳平衡 (PPV:61.6%,rSn:92.4%).
- 在各机构之间发现了显著的PPV差异.
结论:
- 为MID-NET®开发了有效的GIP识别算法.
- 突出了算法准确度和灵敏度之间的固有权衡.
- 该研究提供了一个平衡的算法,以加强药物监测和未来的不良事件检测研究.
相关概念视频
01:22Esophageal Perforation-I: Introduction
91
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
91
01:28Esophageal Perforation-II: Clinical Manifestations and Management
58
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
58