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布里克尔与华莱士尿道状缩:一个多机构的倾向性得分匹配分析
Mulham Al-Nader1, Ulrich Krafft1, Jochen Hess1
1Department of Urology, University Hospital Essen, Essen, Germany.
概括
布里克和华莱士技术用于尿道形解剖,具有相似的狭窄率. 然而,华莱士技术与更多的双边上路干涉有关,增加了单元损害的风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术技巧 手术技巧
- 在瘤学瘤学.
背景情况:
- 尿路转移 (UD) 是激进囊切除术后的一个关键程序.
- 泌尿管内瘤是UD的一个关键步骤,通常采用布里克和华莱士技术.
- 结形成仍然是影响长期结果的重大并发症.
研究的目的:
- 为了比较布里克和华莱士技术之间的狭窄率,用于尿道形解剖.
- 为了确定与尿路肠道狭窄 (UES) 形成相关的风险因素.
主要方法:
- 在两个大学医院接受UD的740名患者的回顾性分析.
- 布里克和华莱士组的倾向匹配分析 (1:1比),考虑各种临床和病理因素.
- 多变量考克斯回归分析以确定UES的预测因素.
主要成果:
- 布里克 (12%) 和华莱士 (14.4%) 组之间的整体UES率没有显著差异 (p=0.56).
- 华莱士组 (10.7%) 与布里克组 (6.2%) 相比,双边上道感染的发生率显著更高 (p=0.00).
- 之前的放射治疗,T4盆腔恶性瘤和结节阳性疾病是UES的独立预测因素.
结论:
- 选择尿道形解剖技术 (布里克与华莱士) 不会独立地影响整体收缩率.
- 在解过程中将两个单元转换为一个单元,与双边上道感染的风险增加有关.
- 识别和减轻风险因素,如先前的放射治疗,对于预防UES至关重要.
相关概念视频
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Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
McNemar's Test
McNemar's Test is a nonparametric statistical test used to determine if there is a significant difference in proportions between two related groups when the outcome is binary (e.g., yes/no, success/failure). It is beneficial when we have paired data, such as pre-test/post-test designs, where the same subjects are measured under two different conditions. The test is named after the statistician Quinn McNemar, who introduced it in 1947. It is commonly used in situations where subjects are...

