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在神经退行性疾病中的血生物标志物的病理和认知相关物

Katheryn A Q Cousins1, Jeffrey S Phillips1, Sandhitsu R Das1

  • 1Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|April 22, 2024
PubMed
概括

血生物标志物,包括化陶氏181 (p-tau181),GFAP和NfL,可以准确检测阿尔茨海默病的病理学. 较高的NfL水平预测粉样蛋白阳性和粉样蛋白阴性个体的认知衰退速度更快.

关键词:
与AD相关的痴呆症 (ADRD)阿尔茨海默氏症 (AD) 是一种疾病.认知能力下降 认知能力下降状纤维酸性蛋白质 (GFAP) 是一种神经纤维光链 (NfL) 是指神经纤维光链.酸化的181 (p-tau181) 是一种化181化合物.血生物标志物 血生物标志物

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