外耳炎的诊断标准和核心结果制定:COSNOE Delphi共识研究
Sirat Lodhi1, Kirsty Dodgson2, Michael Dykes3
1Department of Otolaryngology, Manchester Royal Infirmary, UK.
The Journal of laryngology and otology
|April 22, 2024
概括
这项研究建立了标准化诊断标准和内性外耳炎 (NOE) 的核心结果,以改善研究和患者护理.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 医学研究方法学 医学研究方法学
背景情况:
- 外耳炎 (NOE) 的诊断和管理缺乏标准化的证据.
- 在NOE研究中,结果报告不一致,阻碍了数据合成.
研究的目的:
- 制定对NOE的共识诊断标准.
- 建立基于国际最佳实践的NOE研究的核心成果集 (COS).
主要方法:
- 系统性文献审查和患者定性研究确定了候选项目.
- 两轮的德尔菲演习和共识会议与多学科利益相关者精细化了项目和定义.
- 该研究已预先注册在有效性试验 (COMET) 中的核心结果测量数据库中.
主要成果:
- 共识诊断标准包括6个主题中的12个项目 (例如,症状,疼痛,调查,持续症状,危险因素,晚期疾病指标).
- 核心结果集 (COS) 包含12个主题中的36个项目 (例如,并发症,生存,治疗,复发).
- 利益相关者同意了基本的诊断项目,不包括次要或可选的标准.
结论:
- 标准化诊断标准和COS在NOE中促进一致的研究报告和数据合成.
- 纳入患者和专业人士的观点确保了利益相关者的全面参与和最佳实践.
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