一个新的视角,急性胰腺炎通过水沟排泄,一个多中心的回顾性研究
Lianjie Lin1, Tao Liu2, Bingli Deng3
1Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China.
Heliyon
|April 22, 2024
概括
偏沟排泄 (PGE) 是评估急性胰腺炎严重程度的可靠指标. 患有PGE的患者的结果更差,并将PGE与其他得分结合起来,改善了严重疾病的诊断准确性.
科学领域:
- 胃肠病学 胃肠病学
- 腹部成像 腹部成像 腹部成像
- 临床医学 临床医学
背景情况:
- 偏沟排泄 (PGE) 是一个潜在的,但未被研究的因素,影响急性胰腺炎的严重程度.
- 评估急性胰腺炎的严重程度对于指导治疗和预测患者的结果至关重要.
研究的目的:
- 评价对沟排泄 (PGE) 在评估急性胰腺炎的严重程度和临床过程中的有用性.
- 确定PGE是否可以作为急性胰腺炎不良结果的独立风险因素.
主要方法:
- 来自三所三级医院的488名急性胰腺炎患者的回顾性分析.
- 根据排泄的程度,将PGE分为三个等级 (0,1,2),进行分类.
- 利用ROC曲线和后勤回归来分析PGE得分的预测值,并确定死亡率,ICU入院和MODS的风险因素.
主要成果:
- 患有PGE的患者的住院费用显著增加,住院时间更长,严重急性胰腺炎 (SAP) 发病率增加,死亡率更高,ICU入院率更高,MODS和感染频率更高.
- >1的PGE得分被确定为ICU入院和MODS的独立风险因素.
- 将PGE得分与BISAP,MCTSI,修改的马歇尔和SOFA得分相结合,提高了预测中度严重和严重急性胰腺炎的严重程度的诊断疗效.
结论:
- 偏沟排泄 (PGE) 为评估中度严重和严重急性胰腺炎患者的严重程度和临床过程提供了可靠和客观的数据.
- 在急性胰腺炎中,PGE是风险分层和管理决策的宝贵工具.
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