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Updated: Jun 28, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

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通过深度学习揭示了病原体的基本和与毒性相关的蛋白质相互作用

Ian R Humphreys, Jing Zhang, Minkyung Baek

    bioRxiv : the preprint server for biology
    |April 22, 2024
    PubMed
    概括

    我们开发了一个深度学习管道来识别细菌蛋白相互作用,发现了数百个涉及必需基因和毒性因素的新复合体. 这有助于理解病原体生物学,并开发新的传染病治疗方法.

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    An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
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