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Updated: Jun 28, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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治疗耐药前列腺癌单细胞分析:细胞表面抗原向疗法的细胞状态变化的影响

Samir Zaidi1,2, Jooyoung Park3, Joseph M Chan1,4

  • 1Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

bioRxiv : the preprint server for biology
|April 22, 2024
PubMed
概括

前列腺癌细胞可以改变身份,导致治疗抵抗力. 这项研究揭示了在这种转变过程中细胞表面标记物的显著变化,影响了向治疗的有效性.

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Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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