一个上升的阴道感官中心的诺亚上腺素路径调节了被动回避记忆的检索
Caitlyn M Edwards1, Inge Estefania Guerrero1, Danielle Thompson1
1Department of Psychology, Program in Neuroscience, Florida State University.
bioRxiv : the preprint server for biology
|April 22, 2024
概括
肠道信号影响行为. 扰乱阴道神经或上腺体通路增加了有条件的被动回避,这表明肠-大脑电路调节了学到的恐惧反应.
科学领域:
- 神经科学是一个神经科学.
- 行为神经科学 行为神经科学
- 肠-大脑轴研究研究
背景情况:
- 内在的反,通常是潜意识的,指导着有动机的行为.
- 阴道感官神经元向孤独管 (cNTS) 的尾部核传递肠道信号,而非上腺 (NA) 神经元.
- 这些神经元投射到前腹侧床核的终端 (vlBNST),影响记忆的巩固和灭绝.
结论:
- 一个肠道虚静脉 afferent-to-cNTSNA-to-vlBNST 电路调节了被学习的被动回避的检索.
- 阴道感官反动态地将整体感知信号与上下文线索集成在一起.
- 这种整合对于引起有条件回避行为至关重要.
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