甲蛋白组学和DNA元编码作为评估人类饮食摄入量的工具
Brianna L Petrone1,2, Alexandria Bartlett1,3, Sharon Jiang1
1Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, United States.
bioRxiv : the preprint server for biology
|April 22, 2024
概括
研究人员探索使用便DNA和蛋白质来追踪食物摄入量. 两种方法都确定了类似的饮食模式,蛋白质分析提供了食物类型之间的细微区别,而不是单独的DNA.
科学领域:
- 营养科学 营养科学
- 生物标志物发现发现
- 代谢学 代谢学 代谢学
背景情况:
- 对食物摄入的客观生物标志物对于营养研究至关重要.
- 目前的方法通常依赖于血液或尿液,但使用DNA的便分析正在出现.
- 便中的食物蛋白质仍然是饮食摄入量的不足探索的生物标志物.
结论:
- 便DNA和蛋白质作为评估饮食摄入量的可行生物标志物.
- 与DNA分析相比,元蛋白质组学为区分食物来源提供了更高的分辨率.
- 这些发现支持开发用于饮食评估的元蛋白质组测试,并突出了便中各种食物分子的实用性.
相关概念视频
01:33Proteomics
7.3K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.3K
02:02Genomics
36.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.3K