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Updated: Jun 28, 2025

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques
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N-甘氨酸对人类IgA2的结构的影响

Valentina Ruocco1, Clemens Grünwald-Gruber2, Behzad Rad3

  • 1Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.

Frontiers in molecular biosciences
|April 22, 2024
PubMed
概括

免疫球蛋白A2 (IgA2) 抗体上的甘氨酸会影响其结构和行为. 移除这些甘氨酸会影响聚合,灵活性和形状,这对于开发先进的IgA疗法至关重要.

关键词:
在IgA抗体.N-链接的甘氨酸.萨克斯 (SAXS) 的时间灵活性 灵活性 灵活性蛋白质组合组件的组合蛋白质的稳定性 蛋白质的稳定性

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