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斑点跟踪全球纵向菌株预测系统性硬化症患者的死亡和心血管事件

Giulia Stronati¹, Federico Guerra¹, Devis Benfaremo²

¹Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Marche University Hospital, Via Conca 71, Ancona 60126, Italy.

European heart journal open

|April 22, 2024

概括

全球纵向菌株 (GLS) 在系统性硬化症 (SSc) 中预测死亡率和住院. 双心室GLS损伤显著增加了SSc患者死亡和住院的风险.

科学领域:

心脏病学心脏病学
类风湿病学类风湿病学
医疗成像医学成像

背景情况:

在全身性硬化症 (SSc) 中,心脏参与是死亡率的重要预测因素.
全球纵向应变 (GLS) 可以检测SSc患者的亚临床心脏功能障碍.
在SSc临床结果中GLS的预后价值需要进一步调查.

研究的目的:

评估左侧和右侧GLS与SSc患者全因死亡率之间的关联.
评估左侧和右侧GLS与SSc患者住院率之间的关联.
确定GLS是否可以作为SSc患者可靠的预后工具.

主要方法:

对164名没有先前存在心脏病的SSc患者进行前性纵向研究.
在入学时测量左和右心室GLS.
死亡率和住院病例的随访时间平均为3年.

主要成果:

双体GLS损伤独立地与增加全因死亡率和住院治疗有关.
与没有或单心室损伤的患者相比,双心室GLS损伤的患者死亡风险增加了4.2至13.9倍.
双心室GLS功能障碍患者的住院发生率明显高.

结论:

双管状GLS是SSc.中可靠的预后标志物.
GLS可以预测SSc患者的死亡率和住院.
GLS是早期检测和监测SSc中的心脏参与的一个有价值的工具.

关键词:

心肌病是一种心肌病.心声回声扫描 (Echocardiography) 是一种心声回声扫描.全球纵向菌株全球纵向菌株脊髓硬化症是什么脊髓硬化症斑点跟踪的跟踪方法系统性硬化症系统性硬化症

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