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Updated: Jun 28, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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通过固体分散和与β-cyclodextrins的复合来增强gefitinib的溶解:体外测试,细胞毒性活性和药片配方

Adel F Alghaith1, Gamal M Mahrous1, Ahmed S Alenazi1

  • 1Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
|April 22, 2024
PubMed
概括

这项研究使用固体分散和复合方法增强了Gefitinib (GEF) 的溶解和生物可用性. 配方显著改善了GEF的成分.

关键词:
复杂化 复杂化 复杂化循环德克斯特林 (Cyclodextrins) 是一种循环德克斯特林.细胞毒性 细胞毒性解散 解散 解散 是一个过程.盖菲提尼布 (Gefitinib) 是一种药物.固体的分散 固体的分散药片配方 药片配方 药片配方

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