在一个社会丰富的环境中,慢性不可预测的压力的生理和行为传染/缓冲效应:初步研究
Evren Eraslan1,2,3, Magda J Castelhano-Carlos1,2, Liliana Amorim1,2,4
1Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Neurobiology of stress
|April 22, 2024
概括
社会压力影响老鼠,显示压力缓冲和传染. 慢性不可预测的压力 (CUS) 影响行为和神经内分泌反应,受到社会伙伴的影响,并可能由催产素调解.
科学领域:
- 神经科学是一个神经科学.
- 行为生物学 行为生物学
- 动物行为 动物行为
背景情况:
- 动物对同类动物的情绪状态表现出敏感性.
- 社会伙伴可以减轻压力反应 (缓冲).
- 压力可以在群体成员之间传播 (传染).
研究的目的:
- 在大鼠中研究社会传染和缓冲现象.
- 在慢性压力下检查行为和神经内分泌机制.
- 在受控群体住房环境 (PhenoWorld) 中评估影响.
主要方法:
- 在被分组的老鼠中利用慢性不可预测的压力 (CUS).
- 与纯压力,天真对照和混合压力/对照组进行比较.
- 测量了生理 (体重,上腺体重),行为 (开放的手臂输入,拥挤) 和神经内分泌 (催产素受体表达) 终点.
主要成果:
- CUS降低了体重增加,开放臂的入口和杏仁体的催产素受体表达,同时增加了上腺体重.
- CUS减少了玩,抚养和孤独的休息行为,但增加了拥挤.
- 在体重和拥挤中观察到压力缓冲;在情绪行为和催产素受体表达中观察到压力传染.
结论:
- 缓冲和传染效应在老鼠的生理学,行为和社会互动中很明显.
- 催产素神经传递可能会调解这些社会压力效应.
- 动物的压力状态会影响其群体伴侣的行为.
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