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perfluoroalkyl sulfonamides (FASA) 的生物积累,也就是说它们的生物积累

Heidi M Pickard¹, Faiz Haque¹, Elsie M Sunderland²

¹Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, United States.

Environmental science & technology letters

|April 22, 2024

概括

perfluoroalkyl sulfonamides (FASA) 在鱼类中积累的水平令人担忧,超过了 perfluorooctanesulfonate (PFOS) 的水平. 这些发现凸显了由于潜在风险,迫切需要将FASA纳入鱼类咨询.

科学领域:

环境化学环境化学
生态毒理学生态毒理学
环境科学环境科学

背景情况:

perfluoroalkyl sulfonamides (FASA) 是 perfluoroalkyl和 polyfluoroalkyl物质 (PFAS) 的前体,广泛用于消费品和消防泡中.
电化学化 (ECF) 制造工艺产生FASA,导致美国许多工厂受到污染.
关于FASA在水生生物,特别是鱼类中的生物积累的数据有限.

研究的目的:

调查ECF AFFF污染下游鱼类中短链FASA (C3-C8) 的存在和生物积累.
为了比较FASA的生物积累因子 (BAF) 与 perfluorooctanesulfonate (PFOS) 的生物积累因子.
评估FASA在人类食用的鱼类和环境咨询中积累的潜在风险.

主要方法:

从已知的ECF AFFF污染区下游的地表水中采集了鱼类样本.
使用先进的分析标准量化了碳链长度C3-C8的FASA.
生物积累因子 (BAF) 为FASA计算,并与PFOSBAF值进行比较.

主要成果:

在所有分析的鱼样中检测到FASA,其度与PFOS相似.
对于FASA的生物积累因子明显高 (1-3个数量级),而不是它们的终端 perfluoroalkyl sulfonates.
鱼类中FASA生物积累超过了各种物种中PFOS的生物积累.

结论:

FASA很容易在鱼中积累,比PFOS具有更大的生物积累风险.
鱼类中FASA的存在值得包括在例行查和鱼类消费建议中.
迫切需要对FASA毒性进行进一步的研究,并建立安全门.

关键词:

perfluoroalkyl sulfonamides (FASA) 是一种多甲基硫胺 (FASA) 的一种类型.生物积累的生物积累鱼类鱼类鱼类鱼类的鱼类鱼类.perfluorooctanesulfonate (PFOS) 是一种氧化硫酸盐 (PFOS) 的类型.它们是前体,前体的前体.

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