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Updated: May 11, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
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A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

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一个小型化的多细胞平台,模仿膜-毛囊屏障的3D结构

Michela Licciardello1,2,3, Cecilia Traldi1,2,3, Martina Cicolini2,4

  • 1La.Di.Spe Bioengineerig, Politecnico di Torino, Department of Mechanical and Aerospace Engineering, Turin, Italy.

Frontiers in bioengineering and biotechnology
|April 22, 2024
PubMed
概括

研究人员开发了一种新型的芯片上的气囊模型来研究肺部疾病. 这种微流体装置精确地模拟了气膜结构和细胞相互作用,推动了新疗法的临床前研究.

关键词:
类似于ECM的基板膜-毛细血管屏障的障碍物一个芯片上的气囊.细胞三培养细胞培养在体外模型模型中的体外模型.

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Author Spotlight: Developing a Microfluidic Lung-on-Chip Model for In-Depth Study of Human Immune Response and Infection Mechanisms10:30

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相关概念视频

Alveoli and Alveolar Ducts01:26

Alveoli and Alveolar Ducts

The respiratory zone of the human body, which stands in contrast to the conducting zone, comprises the structures that actively participate in the exchange of gases. The initiation of this zone is marked by the terminal bronchioles converging into respiratory bronchioles, the tiniest bronchiole classification. The respiratory bronchioles give way to the alveolar ducts that opens into a congregation of alveoli. Actively involved in gas exchange, alveoli resemble tiny sacs similar to clusters of...