甲状腺切除术后甲状腺功能低下症的发生率以及相关的手术前和手术内风险因素
Hadi Afandi Al-Hakami1, Renad M Alsolamy2, Baraa I Awad1
1College of Medicine, Department of Otolaryngology-Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center/Ministry of the National Guard - Health Affairs, Jeddah, SAU.
Cureus
|April 22, 2024
概括
整体甲状腺切除术增加了术后甲状腺功能低下症的风险. 识别患有正常术前副甲状腺激素和水平的患者是预防甲状腺手术后这种常见并发症的关键.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 神经外科 神经外科
背景情况:
- 持续性甲状腺功能低下症是全甲状腺切除术后的常见并发症,导致患者患病率显著,医疗保健成本增加.
- 虽然通常不会致死,但低甲状腺功能障碍症在这种经常进行的内分泌手术后会严重影响患者的生活质量.
研究的目的:
- 为了调查甲状腺切除术后手术后缺甲状腺症的发生率和危险因素.
- 为了确定特定的患者或与甲状腺切除术后低副甲状腺症的发展相关的手术因素.
主要方法:
- 一项回顾性队列研究在沙特阿拉伯吉达国王阿卜杜拉齐兹医疗城进行.
- 分析了2016年7月至2022年8月期间接受甲状腺切除术的192名甲状腺癌患者的数据.
- 使用SPSS版本26的统计分析确定了手术类型,手术前水平和手术后副副甲状腺功能障碍之间的关联.
主要成果:
- 在78.1%的患者中进行了全甲状腺切除术,乳头甲状腺癌是最常见的类型 (88.5%).
- 在手术类型和术后偏甲状腺症之间发现了显著的关联 (p<0.05).
- 低血症发生在76.6%的患者中,手术后的小甲状腺功能下降症在无症状低血症或接受静脉糖酸盐 (p<0.05) 的患者中更高.
- 手术后的低血症,低磁血症和高血症与缺甲状腺症 (p<0.05) 有显著的联系.
结论:
- 在经过全甲状腺切除术的患者中,术后甲状腺功能低下的发病率显著更高.
- 正常的术前副甲状腺激素 (PTH) 和 (Mg) 水平被确定为与风险增加相关的重要因素.
- 识别这些手术前的指标对于制定策略来最大限度地减少甲状腺切除术后的甲状腺功能低下症至关重要.
相关概念视频
The Parathyroid Glands
2.1K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
2.1K
Hormones and Bone Tissue
2.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K


