老年人手术前睡眠障碍和手术后痴呆症之间的关联:一个回顾性队列研究
Hao Guo1, Li-Heng Li2, Xiao-Hong Lv1
1Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Nature and science of sleep
|April 22, 2024
概括
在老年手术患者中,手术前睡眠障碍显著增加了手术后狂妄症 (POD) 的风险. 解决先前存在的睡眠问题可能是预防POD的关键.
科学领域:
- 老年医学 老年医学
- 麻醉学 麻醉学
- 睡眠医学 睡眠医学
背景情况:
- 手术后睡眠障碍是手术后痴呆症 (POD) 的已知危险因素.
- 预先存在的睡眠障碍对老年手术患者的POD风险的影响仍未得到充分探索.
研究的目的:
- 调查手术前睡眠障碍与非心脏手术的老年患者中POD发生率之间的关联.
主要方法:
- 对489名老年患者进行了回顾性队列研究.
- 根据手术前失眠症状或睡眠疼痛得分,患者被分为睡眠障碍 (SD) 和非睡眠障碍 (NSD) 组.
- 使用了倾向性得分匹配和多变量逻辑回归分析.
主要成果:
- 在SD组中观察到较高的POD发病率 (16.0%对6.7%不匹配;17.0%对6.2%匹配).
- 在SD组中,手术后睡眠质量较差,疼痛得分较高.
- 术前睡眠障碍被确定为POD的一个独立风险因素 (OR,3.03;P=0.034).
结论:
- 预先存在的睡眠障碍与老年手术患者的POD发病率增加有关.
- 需要进一步的研究来确定改善手术前睡眠质量是否可以减轻POD风险.
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