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Updated: Aug 2, 2026

Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation
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编程-寡核酸纳米组件,用于设计具有强效免疫原性的新抗原疫苗

Zhichu Xiang1,2, Jianhua Lu1, Shangrui Rao1

  • 1Department of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, China.

Theranostics
|April 22, 2024
PubMed
概括

这项研究提出了一种新的无载体新抗原纳米疫苗. 工程化纳米疫苗有效地向抗原呈现细胞 (APC) 输送新抗原和辅助剂,增强抗瘤免疫力,毒性最小.

关键词:
组装的组装组装的组装.免疫疗法 免疫疗法纳米疫苗的使用方法新抗原是一种新抗原.类编程编程是什么?

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siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the ATP-dependent...