死亡率,住院和心脏干预在患有心房的年龄<65岁的患者
Aditya Bhonsale1, Jianhui Zhu2, Floyd Thoma2
1Division of Cardiac Electrophysiology (A.B., K.K., A.V., N.A.E., S.S., S.J.), University of Pittsburgh Medical Center, PA.
Circulation. Arrhythmia and electrophysiology
|April 22, 2024
概括
年轻的心房患者面临重大风险,包括更高的死亡率和心力衰竭,中风和心肌梗塞的住院病例增加. 对这一群体来说,积极管理风险因素和并发症至关重要.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 65岁以下心房动 (AF) 患者的临床过程和长期结果尚不清楚.
- 了解年轻AF患者风险因素 (RF) 和并发症的负担对于有效管理至关重要.
研究的目的:
- 调查风险因素负担,临床过程和65岁以下心房患者的长期结果.
- 为了将65岁以下的AF患者的死亡风险与没有AF的匹配队列进行比较.
主要方法:
- 在2010-2019年期间评估的成年AF患者 (n=67,221) 的回顾性分析.
- 利用电子健康记录和行政数据来识别风险因素,并发病症和结果.
- 在AF患者65岁以下的死亡率与没有AF的大队伍 (n=918,073) 的死亡率进行比较.
主要成果:
- 近四分之一的AF患者年龄在65岁以下,有相当大的心血管风险因素和并发症.
- 与那些没有AF的患者相比,患有AF <65岁的患者的全因死亡率显著更高.
- 在年轻的AF患者中观察到心肌梗塞,心力衰竭和中风的住院风险增加,心力衰竭和高血压的年龄相关相互作用.
结论:
- 65岁以下的AF患者具有显著的并发症负担和相当大的长期死亡风险.
- 这些患者面临着因主要心血管事件而住院的风险大幅增加.
- 对年轻的AF患者来说,需要对风险因素和并发症进行积极的评估和管理.
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