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Updated: Jun 28, 2025

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通过线性扩散寻找RNAase E在RNA中的分裂点:来自单分子FRET的直接证据

Tithi Banerjee1, Eli Rothenberg2, Joel G Belasco1

  • 1Department of Microbiology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

Nucleic acids research
|April 22, 2024
PubMed
概括

观察到,RNase E是一种降解细胞转录的酶,在称为一维扩散的过程中沿着RNA滑动. 这种运动是双向的,并以离散的步骤发生,有助于RNase E在RNA分子上找到分离点.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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