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Updated: Jun 28, 2025

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
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Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation

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卡斯帕斯-3-响应,化双等价瓶刷聚合物

Hadiqa Zafar1, Bin Liu1, Hung V-T Nguyen1

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

ACS macro letters
|April 22, 2024
PubMed
概括

这项研究引入了含有的双价瓶刷聚合物 (BBPs),当被caspase-3分裂时会释放光信号. BBP骨干长度和左边位置控制酶可访问性和信号响应.

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Measuring Caspase Activity Using a Fluorometric Assay or Flow Cytometry

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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