相关实验视频

Updated: Jun 28, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

9.6K

一种选择性纤维细胞生长因子受体1/2 PROTAC降解剂,具有抗瘤活性

Ying Kong1, Xinyue Zhao2, Zhaofu Wang3

  • 1Fudan University, China.

Molecular cancer therapeutics
|April 22, 2024
PubMed
概括

一种新型的蛋白质分解向嵌合体 (PROTAC) 分子BR-cpd7选择性向纤维细胞生长因子受体1和2 (FGFR1/2) 以抑制癌细胞增殖. 这种有针对性的方法在治疗由FGFR1/2异常驱动的癌症方面表现有前途.

更多相关视频

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs10:44

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

13.2K
A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells05:29

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells

Published on: March 28, 2021

2.8K

相关概念视频

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.6K