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融合的表观遗传进化驱动急性髓性白血病的复发

Kevin Nuno1,2,3,4, Armon Azizi2,3,4,5, Thomas Koehnke2,3,4

  • 1Cancer Biology Graduate Program, Stanford University School of Medicine, Stanford, United States.

eLife
|April 22, 2024
PubMed
概括

急性髓性白血病 (AML) 的复发可以在没有遗传变化的情况下发生,由表观遗传进化驱动. 不同的白血病细胞克隆在复发时显示类似的表观遗传模式,表明治疗后的融合进化.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.癌症生物学 癌症生物学表观遗传学是指表观遗传学.遗传学 遗传学 遗传学 是一个基因组学就是基因组学.人类 人类 人类 人类 人类 人类 人类这是一个复发的复发.

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