甘的化学酶转化为乳酸和甘油酸
Yue Ma1,2, Tianzhen Li2, Zijian Tan2
1State Key Laboratory of Food Nutrition and Safety, College of Biotechnology, Tianjin University of Science and Technology, No 9, 13th, Avenue, Tianjin Economic and Technological Development Area (TEDA), Tianjin, 300457, China.
Bioresources and bioprocessing
|April 22, 2024
概括
本研究介绍了一种化学酶方法,用于将原始甘油转化为乳酸和甘油酸. 该过程有效地通过酶产生1,3-二基亚 (DHA),然后通过化学转化转化为有价值的酸.
科学领域:
- 生物技术是生物技术.
- 绿色化学 绿色化学
- 生物催化剂是一种生物催化剂.
背景情况:
- 作为生物柴油副产品的甘油,需要高效的价值化成高价值化学品.
- 开发可持续的化学合成催化过程至关重要.
研究的目的:
- 建立化学酶级联反应,将甘油转化为乳酸和甘油酸.
- 为了优化酶系统,将糖转化为1,3-二氧化 (DHA).
主要方法:
- 使用糖脱酶 (GldA) 和NADH氧化酶 (SpNoxK184R) 与共酶循环系统将糖酶转化为DHA.
- 使用NaOH或NaClO2进行化学催化,将DHA转化为乳酸和甘油酸.
主要成果:
- 从糖醇中获得1,3-二氧化 (DHA) 的92.3%的产量.
- 从DHA.获得高产的乳酸 (72.3%) 和甘油酸 (78.2%).
结论:
- 开发的化学酶级联反应是一种有效的策略,用于将糖转化为乳酸和甘油酸.
- 这种方法为从生物柴油副产品中生产高价值化学品提供了一个可持续的途径.
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